Drug and Alcohol
Understanding Schedule 3 Drugs

Learn about Schedule 3 Drugs, their uses, risks, and potential for addiction. Find out if they're safe and how to seek help for substance misuse or dependence.
Many people believe Schedule 3 Drugs are safe because they have medical uses. However, these substances still carry a risk of dependence and misuse. If you or a loved one is struggling with substance abuse, the dangers should not be overlooked.
Even though these drugs are less restricted than Schedule 1 or 2 substances, they can still lead to addiction, impacting mental health, relationships, and daily life. Without proper help, misuse can quickly spiral out of control. At The Edge Treatment Center, we offer compassionate, personalized treatment to help you or your loved one overcome addiction. Recovery is possible.
Definition
Schedule 3 drugs are substances that have accepted medical uses but also have a potential for abuse and dependence. They are classified under the Controlled Substances Act (CSA), which regulates drugs based on their risk of abuse, medical value, and potential for dependence.
Definition and Criteria for Schedule 3 Classification
A drug is classified as Schedule 3 if it meets the following criteria:
It has recognized medical uses.
It has a moderate to low potential for physical dependence but a higher potential for psychological dependence.
It has a lower risk of abuse compared to Schedule 1 and Schedule 2 drugs.
Examples
Ketamine
Originally developed as an anesthetic, ketamine is used in medical settings for pain relief and sedation.
It has also gained popularity as a treatment for depression and PTSD, but misuse as a party drug (often called "Special K") has raised concerns.
Abuse of ketamine can cause hallucinations, dissociation, and memory loss.
Anabolic Steroids (e.g., Testosterone)
These substances are prescribed for conditions such as hormone deficiencies or muscle-wasting diseases.
Athletes and bodybuilders often misuse them to enhance performance and muscle growth.
Long-term misuse can lead to liver damage, mood swings, and heart problems.
Buprenorphine
Used in opioid addiction treatment, buprenorphine helps reduce cravings and withdrawal symptoms.
Unlike full opioids, it has a "ceiling effect," meaning it does not cause the same high at increased doses.
Although it is safer than many opioids, it can still be misused, leading to dependence.
Dronabinol (Synthetic THC)
A synthetic form of tetrahydrocannabinol (THC), the active ingredient in cannabis.
Prescribed to treat nausea in chemotherapy patients and appetite loss in AIDS patients.
While it has medical benefits, misuse can lead to dizziness, paranoia, and dependence.
Potential for Abuse and Addiction

Schedule 3 drugs are classified as having moderate to low physical dependence but high psychological dependence. This means that while they may not cause severe withdrawal symptoms like heroin or fentanyl, they can still create intense cravings and compulsive use, particularly in individuals with a history of substance abuse.
Factors Contributing to Misuse
Euphoria-Inducing Properties
These drugs have psychoactive effects that can create a sense of euphoria or relaxation, making them attractive for recreational use.
Ketamine, for instance, is abused for its hallucinogenic and dissociative effects, while buprenorphine can produce a mild opioid-like high in non-medical use.
Accessibility Due to Medical Legitimacy
Because these drugs have accepted medical uses, they are more widely prescribed and available.
This accessibility increases the likelihood of misuse, especially when prescriptions are shared, obtained illegally, or taken in higher doses than prescribed.
Athletes and bodybuilders often misuse anabolic steroids without medical supervision to enhance performance and muscle growth.

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Risks and Side Effects
While these drugs serve important medical purposes, misuse can lead to serious health risks. These substances carry a lower abuse potential than Schedule 1 and 2 drugs but still pose short-term and long-term dangers, including addiction, mental health issues, and physical harm.
Short-Term and Long-Term Health Risks
Short-Term Risks:
Nausea and dizziness – Common with drugs like ketamine and dronabinol.
Impaired judgment and coordination – This can lead to accidents and risky behavior.
Mood swings and aggression – Especially with anabolic steroids.
Respiratory depression – High doses of buprenorphine can slow breathing.
Hallucinations and dissociation – Often seen with ketamine misuse.
Long-Term Risks:
Liver and kidney damage – Common with steroid misuse.
Heart disease and high blood pressure – Anabolic steroid use increases cardiovascular risks.
Cognitive impairment – Chronic ketamine misuse can cause memory loss and difficulty concentrating.
Hormonal imbalances – Long-term steroid use can lead to infertility and severe mood disorders.
Increased risk of overdose – Even though they are less potent than opioids like fentanyl, misuse can still lead to serious medical emergencies.
Psychological and Physical Dependence
Although Schedule 3 drugs are considered to have a moderate potential for dependence, long-term use can still lead to addiction.
Physical Dependence – The body adjusts to the drug over time, requiring higher doses to achieve the same effects. Withdrawal symptoms, such as fatigue, irritability, and nausea, may appear when stopping use.
Psychological Dependence – Individuals may crave the drug and feel they cannot function without it, especially in the case of ketamine or steroids.
Impact on Mental Health and Overall Well-Being
Misuse of these drugs can have devastating effects on mental health, including:
Depression and anxiety are common in those abusing steroids or buprenorphine.
Psychosis and paranoia – This can result from long-term misuse of ketamine or dronabinol.
Aggression and mood instability – Anabolic steroid misuse can cause “roid rage,” leading to violent outbursts.
Social and relationship problems – Drug misuse can cause isolation, trust issues, and conflicts with family and friends.
Regulations and Legal Implications
Schedule 3 drugs are controlled under the Controlled Substances Act (CSA) due to their moderate risk of abuse. While they have accepted medical uses, strict regulations exist to prevent misuse.
Prescription Guidelines and Restrictions
Must be prescribed by a licensed healthcare provider.
Refills are limited to five times within six months.
Pharmacies and providers must follow strict tracking and storage rules.
Consequences of Illegal Possession or Distribution
Possession without a prescription can lead to fines or jail time.
Illegal sale or distribution is a felony with severe penalties.
DUI charges apply if misused while driving.
Recognizing Signs of Abuse
While these drugs have medical benefits, misuse can lead to dependence and addiction. Recognizing the warning signs of abuse can help prevent serious health risks and legal consequences.
Behavioral and Physical Indicators of Misuse
Behavioral Signs:
Taking higher doses than prescribed.
Seeking multiple prescriptions from different doctors (doctor shopping).
Secretive behavior or mood swings.
Neglecting responsibilities or social withdrawal.
Physical Signs:
Drowsiness, dizziness, or slurred speech.
Unexplained weight loss (steroid abuse).
Changes in appetite or sleep patterns.
Increased tolerance requires higher doses for the same effect.
Legitimate Use Vs. Abuse
Legitimate use follows a doctor’s instructions, with stable doses and medical supervision.
Abuse involves self-medicating, exceeding prescribed doses, or using without a prescription.

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Treatment and Support Options for Schedule 3 Drug Addiction
Overcoming addiction to these drugs requires a comprehensive treatment approach that addresses both physical dependence and psychological factors. With the proper support, recovery is possible.
Detoxification
The first step in treatment, detox helps safely remove the drug from the body.
Medical supervision can manage withdrawal symptoms and prevent complications.
Counseling and Behavioral Therapies
Cognitive Behavioral Therapy (CBT) helps individuals recognize and change harmful thought patterns.
Group and individual therapy provide emotional support and coping strategies.
Medication-Assisted Treatment (MAT)
Buprenorphine may be used to treat opioid dependence while preventing withdrawal.
Other medications can help manage cravings and stabilize recovery.
The Role of Recovery Treatment Centers
The Edge Treatment Center provides personalized care, including:
Tailored treatment plans based on individual needs.
Holistic therapies such as mindfulness, exercise, and nutritional support.
Long-term recovery support to prevent relapse.
Struggling with Schedule 3 Drug Addiction? We Can Help
While Schedule 3 drugs have medical benefits, misuse can lead to dependence, health risks, and legal consequences. Recognizing the signs of abuse and seeking professional treatment are crucial steps toward recovery.
At The Edge Treatment Center, we provide personalized care, including detox, therapy, and long-term support to help individuals break free from addiction. If you or a loved one is struggling, you don’t have to face it alone. Contact us today—we’ll help you regain control and build a healthier, addiction-free life.

We’re Here To Help You Find Your Way
If you or a loved one is struggling with addiction, there is hope. Our team can guide you on your journey to recovery. Call us today.
Written by

The Edge Treatment Center
Reviewed by

Chief Clinical Officer
Drug and Alcohol
May 20, 2025
FAQ
Frequently Asked Questions
They are substances with accepted medical uses and a moderate to low potential for physical and psychological dependence. They are less prone to abuse compared to Schedule 1 and 2 drugs but still require regulation to prevent misuse.
Yes, misuse of these drugs can result in addiction. While they have legitimate medical applications, improper use—such as taking higher doses or using without a prescription—can lead to physical dependence and addiction.
These drugs require a prescription from a licensed healthcare provider. Prescriptions can be refilled up to five times within six months. Strict tracking and storage protocols are in place to prevent misuse and ensure patient safety.
If you suspect misuse, look for signs like behavioral changes, secrecy, or physical symptoms. Encourage the individual to seek professional help. Recovery centers like The Edge Treatment Center offer personalized treatment plans to address addiction and support recovery.
These drugs have a lower potential for abuse compared to Schedule 1 and 2 substances but a higher potential than Schedule 4 drugs. They balance accepted medical use with moderate abuse potential.