Opioid Addiction - Drug and Alcohol

M523 Pill: What It Is, How It’s Used, and What’s in the M 523 Pill

What is the M523 Pill?

Percocet, an opioid painkiller, comes in several forms. One of them is the M523 pill. Learn more about this opioid drug in our blog.

Written by

brian-mooreBrian Moore

Content Writer

Reviewed by

jeremy-arztJeremy Arzt

Chief Clinical Officer

Opioid Addiction

Drug and Alcohol

September 8, 2023

The M523 pill has two active ingredients: acetaminophen and oxycodone hydrochloride, an opioid painkiller. It is routinely recommended to treat moderate to severe pain. Let us dig into the uses, potential side effects, and precautions related to the M523 tablet in this thorough piece of information to offer you a better knowledge of this drug and how it may be used safely and successfully over some time. 

What’s in the M523 Pill?

The M523 pill is a small, round tablet that is typically white in color. The code "M523" is imprinted on one side for easy identification. The tablet contains two drugs: acetaminophen and oxycodone hydrochloride. Acetaminophen is the non-opioid option for relieving pain and reducing temperature, whereas oxycodone is the opioid analgesic.

How Does the M523 Pill Work?

The M523 pill works through the combined action of its two active ingredients. Acetaminophen relieves pain by suppressing the generation of molecules in the body that are responsible for conveying pain signals. It can also assist in lowering fever by working on the hypothalamus in the brain. Oxycodone, on the other hand, attaches to opioid receptors in the central nervous system, causing pain signals to be blocked and relieving effects to be produced.

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Dosage of M523

The M523 tablet dose may vary according to the degree of the pain, the individual's response to the drug, and other factors like age and overall health. A M523 pill consists of:

  • 325 mg of acetaminophen

  • 10 mg of oxycodone hydrochloride

You must follow your healthcare professional's dosing guidelines. Taking more than authorized might result in significant health consequences, including overdose.

  • The M523 tablet should be consumed whole, without crushing, chewing or snorting the pill

  • The typical starting dose for adults is one tablet every 4 to 6 hours as needed for pain relief.

  • The maximum daily dosage of acetaminophen in the M523 pill should not exceed 4,000 milligrams to avoid potential liver damage.

  • Your trusted doctor may adjust the dosage based on your needs and medication response.

  • Older people or those with liver or kidney problems may require lower dosages to prevent complications.

Brand Names of the M523 Pill

Like many pills, M523 is used under many different brand names. They include

  • Endocet

  • Nalocet

  • Percocet

  • Primalev

  • Roxicet

  • Xartemis XR

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Potential Side Effects of the M523 Pill

Like any medication, the M523 pill may cause specific side effects. It is imperative to indulge in a medical suggestion whenever you face any side effects. Here are some of the potential side effects that can affect a human body after having the M523 pill:

Nausea and Vomiting

Some individuals may experience gastrointestinal disturbances such as nausea and vomiting after taking the M523 pill. Taking the medication with food or milk can help subside these symptoms.


Opioid-based medications like the M523 pill can cause constipation, a common side effect. Increasing fluid intake, eating a high-fiber diet, and engaging in regular workout sessions can easily help to sail through the problem of constipation quickly. 

Drowsiness and Dizziness

The M523 pill may cause drowsiness or dizziness, especially when starting the medication or with higher dosages. It is critical to avoid tasks that demand attentiveness, including working on heavy machinery and driving a vehicle, unless you know how the specific medicine affects your system. 

Respiratory Depression

Opioids can slow down breathing, leading to respiratory depression. This is especially common at larger dosages or when taken with other respiratory depressant medicines. If you have breathing difficulties or are breathing heavily, get medical treatment immediately.

Itching or Rash

Some individuals may develop itching or a skin rash after taking the M523 pill. Make sure to seek medical treatment immediately if you face issues like facial swelling, lips numbing, etc. 


Headaches may occur as a side effect of the M523 pill. Suppose you face the problem of severe headaches in a consistent manner. In that case, you must consult a nearby doctor urgently. 

Sweating and Flushing

Some individuals may experience increased sweating or flushing of the skin while taking the M523 pill. These symptoms may vanish with time and settle slowly and steadily.

Mood Swings

Opioids can affect mood and mental health. Some people may sense exhilaration, while others may deal with mood swings, anxiety, or sadness. Any substantial changes in mood or mental health should be immediately reported to your doctor without any second thoughts. 

Urinary Retention

This pill can affect bladder function and cause difficulty in urination or urinary retention. If there is any change in your urinary well-being, you should inform the doctor as soon as possible. 

Dependence and addiction: Prolonged use of opioids, including the M523 pill, can lead to physical dependence and, in some cases, addiction. Never take the prescription for granted; do not alter the medicated plan without medical consent.

Does the M523 Pill Have Withdrawal Symptoms?

Yes – the M523 pill contains oxycodone, which is an addictive opioid. For someone who has been taking the M 523 pill for a long time and stops without tapering off, they may experience withdrawal symptoms. This happens because our bodies can rapidly become dependent on opioids like oxycodone, and the body is thrown into shock when oxycodone is no longer in our system.

Withdrawal effects of the M525 pill include:

  • Anxiety, agitation, and depression

  • Diarrhea, nausea, and vomiting

  • Body aches

  • Flu-like symptoms

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Precautions to Take While Taking the M523 Pill

Ensure your doctor knows of any pre-existing medical issues, allergies, or drugs you are taking before taking the M523 tablet. People with a history of drug misuse, lung illness, or liver disease may be at a higher risk of negative effects. It is critical to take the medication exactly as recommended and to avoid alcohol or other medications that may increase the prescription's sleepy effects.

People allergic to acetaminophen, oxycodone, or any other opioid drug should not use the M523 pill as well. Here are some other guidelines you should strongly consider:

Consume Under Medical Supervision

M523 is a prescription drug that should only be taken under the guidance of a healthcare practitioner. Follow your doctor's directions for dose, length of therapy, and any special precautions or warnings.


Inform your healthcare expert if you have any known allergies or hypersensitivity to opioids, acetaminophen, or other ingredients in the M523 pill. This will help prevent any potential allergic reactions.

Other Medications

Inform your doctor about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Certain medications, such as sedatives, tranquilizers, or other opioids, may interact with the M523 pill and lead to adverse effects. Your doctor can assess potential drug interactions and adjust your treatment plan accordingly.

Medical Conditions

Discuss your medical history and pre-existing conditions with your healthcare professional before starting M523. Inform the doctor about any liver or kidney problems, respiratory disorders, history of substance abuse, or mental health conditions. These factors may affect the safety and effectiveness of the medication.

Avoid Alcohol

Alcohol can intensify the sedative effects of the M523 pill, leading to excessive drowsiness, dizziness, or impaired judgment. It is advisable to avoid alcohol while taking this medication to minimize the risk of adverse effects.

Pregnancy and Breastfeeding

If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of taking the M523 pill with your gynecologist. Opioids can have potential risks to the fetus or newborn, and alternative pain management options may be considered to decrease any pain a person has. 

Driving and Operating Machinery

The M523 pill may cause drowsiness, dizziness, or impaired coordination. Avoid driving or operating heavy machinery until you know how the medication affects you. It is essential to prioritize safety and prevent accidents in such conditions.

M523: Potential Drug Interactions

Antidepressants, antifungal therapies, and sedatives, among other drugs, may interact with the M523 pill. These combinations may increase the risk of side effects or reduce the effectiveness of the M523 pill. Notify your doctor about all medications you are taking to ensure the safe and optimal usage of the M523 pill.

Other drugs that shouldn’t be mixed with the M 523 tablet include:

Central Nervous System (CNS) Depressants

Combining the M523 pill with other CNS depressants, such as sedatives, tranquilizers, or alcohol, can increase the risk of sedation, respiratory depression, and impaired coordination. This can lead to extreme drowsiness, dizziness, and even coma. Avoid combining M523 with other medications that have sedating effects unless specifically instructed by your doctor.

Monoamine Oxidase Inhibitors (MAOIs)

MAOIs are an antidepressant medication. Combining MAOIs with the M523 pill can lead to a potentially life-threatening condition known as serotonin syndrome. Symptoms of serotonin syndrome include agitation, confusion, rapid heartbeat, elevated blood pressure, tremors, and fever. MAOIs should be discontinued at least 14 days before starting treatment with the M523 pill.


Certain antidepressant medications, such as selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), can interact with the M523 pill and increase the risk of serotonin syndrome. Inform your doctor if you are taking any antidepressant medications to ensure the safe usage of the M523 pill.


Benzodiazepines are commonly used to treat anxiety and sleep disorders. Combining benzodiazepines with the M523 pill can increase the sedative effects and respiratory depression. This can lead to extreme drowsiness, impaired coordination, and even complete respiratory failure. It is essential to use these medications cautiously and under the guidance of your healthcare provider.

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When to Stop Using the M523 Pill

Suppose you are on M523 medication, and you want to discontinue the same. In that case, keeping some essential factors in mind rather than abruptly discontinuing them is crucial. Certain substances are included in these pills, often used to treat moderate to severe pain. However, this pill is recommended under medical supervision as it may cause serious health issues if not taken under close tracking. 

  • Follow your doctor's orders: The most crucial component of discontinuing the M523 tablet is to follow your doctor's orders. Your healthcare professional is aware of your medical history and pain management requirements. Based on your situation, they will establish the proper length for taking the drug. If you have any concerns or are experiencing any adverse effects, see your doctor before making any adjustments.

  • Gradual tapering: Stopping the M523 tablet abruptly might cause withdrawal symptoms and other issues. A slow tapering process may be recommended by your doctor to avoid this. This entails gradually decreasing the dosage until you ultimately stop taking the drug. Tapering allows your body to acclimatize to the change and reduces withdrawal symptoms.

  • Monitor the pain: Monitor your pain levels and how effectively the medicine handles them when taking the M523 tablet. If you find a considerable improvement in your pain, this might indicate that you can progressively lower the dosage. However, never alter your medicine without first visiting your doctor.

  • Evaluate side effects: Be mindful of any side effects you experience while using M523. Common side effects include drowsiness, constipation, and nausea. If you have any adverse effects, call your doctor immediately. The doctor is the only person who can alter the plan without consent. It would help if you never assumed anything on your own because it can put you in some serious health conditions for life. 

  • Discuss alternative treatments: As your pain improves, your doctor may suggest that you look into alternative pain management options. Physical therapy, non-opioid medicines, or lifestyle modifications might be among them. Collaborate with your healthcare practitioner to choose the optimal method for treating your pain that does not rely primarily on opioids.

  • Avoid self-medication: Never share your M523 medicine with others; never take another person's prescription. Self-medication or using opioids without competent medical supervision is risky and can have significant health implications. Always get personalized guidance from your doctor.

Feel Like M523 Pills Are Taking Over Your Life? The Edge Treatment Center Will Help

If you have recently been feeling like M523 Percocet pills are causing you to spin out of control, you're not alone. You may feel scared or overwhelmed at the thought of having to take this powerful medication on a daily basis for an unknown amount of time. The good news is, there is help available to support you through this tough transition.

The Edge Treatment Center is a highly skilled and experienced addiction treatment center that specializes in treating those with addictions to M523 Percocet pills. Our compassionate team of professionals is equipped to provide you with the individualized care and attention needed to build a solid foundation of sobriety. We also offer a range of services to meet your unique needs, including an intensive outpatient program, medication-assisted treatment (MAT), and access to 12-step support groups.

Our team is dedicated to helping you take control of your life back from the grips of M523 Percocet addiction. Every step of the way, we will work with you to ensure that you are on track and making progress towards lasting recovery and sobriety.

If you or someone you love is in need of help with M523 Percocet addiction, please don't hesitate to reach out to the Edge Treatment Center today. Our team is here to provide you with the resources and support needed to get back on your feet and start living a life free from addiction. We look forward to helping you take control of your life back.

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If you or a loved one is struggling with addiction, there is hope. Our team can guide you on your journey to recovery. Call us today.